Linear Peptide Synthesis|Customized Linear Peptides|High Purity Linear Peptides|Kev tshawb fawb-Peptide
Meta Description
Xav tau siab purity linear peptides?Science-Peptide's Linear Peptide Synthesis kev pabcuam npog 2-189 amino acids, 200+ kev hloov kho los xaiv, milligrams rau kilograms, xa khoom sai hauv 10-15 hnub ua haujlwm. Kev nug yog txais tos.
Dab tsi yog linear peptides?
Ib tug linear peptide yog ib qho amino acid uas txuas rau qhov kawg ntawm cov amino acid kab, tsis muaj cov qauv cyclic. Cov paib peptides, antimicrobial peptides, daim nyias nyias - nkag mus rau peptides, thiab precursors rau cyclic peptides yog tag nrho cov linear peptides.
Linear Peptide Synthesis suab yooj yim, tab sis thaum nws los ua nws, muaj ntau cov potholes - ntev sequences yog ib qho yooj yim rau aggregate, hydrophobic peptides khiav tawm ntawm chav dej thaum purified, thiab cov chaw nrog kev hloov kho tsis tau nyob rau hauv qhov chaw. Peb tau nqis los ntawm cov pas dej ua ntej, thiab peb paub yuav ua li cas mus ncig lawv.
1. Ntev: 2 txog 189 Amino Acids
|
Ntev |
Cov lus nug nquag |
Peb yuav ua li cas txog nws? |
|
luv peptides (2-15) |
Nws yog qhov yooj yim tsis muaj -brainer |
Pa synthesis, siab yield, haum rau siab ntim |
|
Nruab nrab thiab ntev peptides (15-50) |
Ntau hydrophobic amino acids zoo li sib sau ua ke |
Kev kho cov kuab tshuaj system, ntxiv rau solubilizing daim ntawv lo |
|
Ntev peptides (50-100) |
Tsawg synthesis efficiency, nyuaj rau purify |
Segment synthesis, xaiv cov ntu zoo tshaj plaws rau splicing |
|
Ultra-long peptides (>100) |
Tej yam yuav mus tsis ncaj ncees lawm ntawm txhua kauj ruam ntawm txoj kev |
Cov tswv yim tiv thaiv tshwj xeeb, mus txog 189 |
2. Purity: nyob ntawm seb koj ua dab tsi nrog nws
- Crude (70-85%): rau thawj zaug sieving, saib seb leej twg yog active ua ntej, txuag nqi.
- Cov niaj hnub ntshiab (85-95%): feem ntau cov kev sim ntawm tes, raug nqi zoo.
- High purity (95-98%): kev sim tsiaj, kev ua haujlwm tseeb, cov txiaj ntsig zoo dua.
- Ultra-pure (>98%): siv lead ua qauv, NMR, purity Raman.
- Txhua peptide yog nrog los ntawm HPLC thiab MS daim ntawv qhia, qhov purity yog dab tsi. Peb ua Linear Peptide Synthesis, peb tsis ua si.
3. Kev hloov kho: tshaj 200, koj lub npe, peb tau txais nws
- Fluorescent labeling: FITC, TAMRA, Cy5, saib seb peptide nkag mus rau hauv lub cell li cas.
- Affinity labeling: biotin, Nws tag, rau purification los yog nrhiav kom tau.
- Kev hloov kho ruaj khov: PEGylation, fatty acids, txuas ntxiv ib nrab -lub neej.
- Tshaj tawm -kev hloov pauv kev txhais lus: phosphorylation, glycosylation, acetylation, ua raws li lub xeev tiag tiag.
- Cov amino acids tshwj xeeb: D- hom, tsis zoo li qub, isotopically sau npe (15N, 13C).
- Xaus kev hloov kho: amidation, acetylation, dawb acid, ntawm kev thov.
- Qhov twg yog qhov hloov kho koj li Linear Peptide Synthesis xav tau, peb tau ua tiav.
Vim li cas thiaj hu rau peb rau Linear Peptide Synthesis?
1. Peb tau ua qhov no tau 20 xyoo
Linear peptide synthesis yog ib qho txuj ci yooj yim, tab sis muaj ntau qhov sib txawv ntawm cov txuj ci yooj yim. Transmembrane peptides, amyloid peptides, precursors nrog ob peb disulfide bonds - peb tau pom ntau peptides uas nyuaj rau synthesize ntau xyoo. Peb muaj lub tswv yim zoo ntawm cov kab ke uas muaj teeb meem thiab cov xwm txheej twg tuaj yeem cawm tau lawv. Hauv Linear Peptide Synthesis, kev paub yog ib yam dab tsi uas tsis tuaj yeem sau tau hauv ib hnub lossis ob hnub.
2. Muaj ntau tshaj ib txoj kev
Nyob ntawm koj qhov peptide thiab ntau npaum li cas, peb yuav pab koj xaiv:
- Khoom theem synthesis: cov qauv xaiv, lub sij hawm luv luv, haum rau feem ntau linear peptides.
- Ua kua theem synthesis: ntev peptides los yog loj, tus nqi qis.
- Solid-kua hybridization: solid-theem rau cov tawg yooj yim, ua raws li cov kua-theem splicing kom sib npaug zoo thiab nqi.
- Peb tsis yog thawb ib qho thev naus laus zis xwb, peb ua lej rau koj: uas yog tus nqi tshaj plaws -txoj kev zoo rau koj li Linear Peptide Synthesis.
3. Kev tswj kom zoo yam tsis muaj kev ntxhov siab
- MS kom pom tias qhov hnyav molecular puas yog.
- HPLC saib seb puas muaj purity txaus.
- Peptide cov ntsiab lus, endotoxin, noo noo, amino acid tsom xam - ntxiv raws li xav tau.
- Ua Linear Peptide Synthesis, cov ntaub ntawv hais lus rau nws tus kheej, txhua peptide yog cov ntaub ntawv zoo.
4. Lub sij hawm xa tuaj hais rau nws tus kheej
Txheem peptides (<30aa, unmodified) 10-15 working days. The fastest time for expediting is 5 days. For long peptides or peptides with modifications, we will evaluate the peptide before reporting the lead time, and we will actively synchronize the progress in the middle so that you won't have to wait for the peptide. Choose our Linear Peptide Synthesis, delivery is not a problem.
5. Los ntawm me me mus rau qhov loj, tsis muaj kev hloov pauv ntawm cov neeg xa khoom
milligrams nyob rau theem sim, grams nyob rau hauv preclinical scale -nce, kilograms nyob rau hauv zus tau tej cov - peb yuav lis nws tag nrho. Tib qhov project, tib qhov sib koom ua ke, tshem tawm cov teeb meem ntawm re- kev koom ua ke. Peb tuaj yeem ua raws li koj li Linear Peptide Synthesis mus txog thaum kawg.
Qhov twg tuaj yeem siv Linear Peptides?
|
Tshawb nrhiav cov lus qhia |
Cov kev xav tau |
Peb yuav ua li cas |
|
Tshuaj ntsuam xyuas |
Ib pawg ntawm analogs los ntsuas qhov kev ua ntawm |
Siab -throughput synthesis, xa sai |
|
Cell -peptides nkag mus |
Nrog cov cim kom pom kev noj |
FITC/TAMRA labeling, purity >95%. |
|
Antimicrobial peptides |
Sequences nrog siab sieve kev ua si |
Tswj purity, batch sib xws |
|
Kev taw qhia txoj kev |
Substrate peptides, inhibitors |
Tej zaum yuav yog phosphorylated, acetylated |
|
Cov txheej txheem biology |
NMR, siv lead ua |
High purity, isotopically sau npe |
|
Immunology |
Antigenic peptides, epitope localization |
Biotin{0}} tau sau npe rau ELISA |
|
Khoom siv science |
Tus kheej - sib dhos peptides |
Sequential precision tswj |
Txawm hais tias koj siv Linear Peptide Synthesis nyob qhov twg, peb muaj kev daws teeb meem rau koj.
Kev xa khoom thiab kev tswj xyuas zoo
- Daim ntawv xa tuaj: lyophilized hmoov, centrifuge raj lossis vials.
- Cov ntaub ntawv nrog: COA (HPLC profile + MS spectrum).
- Kev ntsuam xyuas yeem: peptide cov ntsiab lus, endotoxin, noo noo, amino acid muaj pes tsawg leeg.
- Customized Ntim: Dispensing, labeling, mixing as per koj xav tau.
- Txhua Linear Peptide Synthesis khoom raug tshuaj xyuas ua ntej ua zaub mov xa tuaj.
Peb zaj dab neeg tseeb
Case 1: Antimicrobial peptide program ntawm lub koom haum tshawb fawb
Asked for 30 linear peptides of 10-20aa to screen for antimicrobial activity. delivered in 2 weeks, all >90% ntshiab. Lawv tau tshuaj xyuas 5 qhov zoo thiab luam tawm tsab xov xwm tom qab. Qhov kev pab cuam Linear Peptide Synthesis cawm lawv tsawg kawg ib hlis ntawm lub sijhawm tos.
Case 2: Permeable peptide tshawb fawb los ntawm ntau lub teb chaws kws tshuaj
A 25aa membrane-penetrating peptide with FITC labeling. The sequence is hydrophobic, so it is easy to be aggregated during synthesis. We added a temporary solubilizing tag and removed it after purification, and finally the purity was >95% thiab cov ntawv sau ua haujlwm tau siab, yog li kev sim ntawm tes tau ua tiav zoo. Cov neeg siv khoom tau hais tias qhov zoo ntawm no Linear Peptide Synthesis yog qhov ruaj khov dua li ntawm lawv cov khoom muag dhau los.
Case 3: Structural Biology Subjects at a Domestic University
We want a 15N-labeled linear peptide to do NMR, introduce isotopes accurately, and the purity is >98%, thiab cov neeg siv khoom tau txais kev pom meej meej thiab daws cov qauv. Peb tau ntsib nyob rau hauv hom kev xav tau Linear Peptide Synthesis.
Tham txog koj cov kev xav tau?
Txawm hais tias nws yog ob peb siab -purity peptides rau qhov kev sim tseem ceeb lossis ib pawg loj uas tau tsim los rau kev tshuaj ntsuam, koj tuaj yeem tham. Xaiv Kev Tshawb Fawb-Peptide's Linear Peptide Synthesis pabcuam txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhuam hniav
Kuv xav kom koj qhia kuv:
peptide ua ntu zus
Yuav thov npaum li cas (mg/g/kg)
purity xav tau
luas los tsis luas
Thaum twg koj xav tau nws?
Muab ib qho kev txiav txim rau koj thiab kev npaj xa tuaj hauv 24 teev.